Because its mechanism of action is mechanical, Plenity is considered a medical device rather than a drug. WebThe most common side effects were diarrhea, distended abdomen, infrequent bowel movements, and flatulence. Watch the video below to learn more. The most common side effects were diarrhea, distended abdomen, infrequent bowel movements, and flatulence. How often a drug interaction occurs, and your risk for a drug interaction, also depends upon factors such as: Don't forget that alcohol, caffeine, and illegal drugs of abuse can lead to serious drug interactions, too. Do I need to see a doctor in person to get Plenity? Type a drug name in the box above to get started. Within 14 days of stopping an MAOI intended to treat psychiatric disorders. For these reasons, Plenity is considered a medical device rather than a drug, leading to a different threshold for approval. doi: 10.1002/14651858.CD008650.pub2. See permissionsforcopyrightquestions and/or permission requests. Check for drug interactions and save your list for future reference. Only human studies were used for drug interaction, efficacy, and safety data. Plenity is not dispensed in pharmacies. Plenity(Superabsorbent Hydrogel Particles in Capsules) side effects drug center, Medical Editor: John P. Cunha, DO, FACOEP. Note: Multiple pictures are displayed for those medicines available in different strengths, marketed under different brand names and for medicines manufactured by different pharmaceutical companies. The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. This interaction can occur with the commonly used statins to lower cholesterol, like atorvastatin, lovastatin, or simvastatin. Pill Identifier Tool Quick, Easy, Pill Identification, Drug Interaction Tool Check Potential Drug Interactions, Pharmacy Locator Tool Including 24 Hour, Pharmacies. This may be due to the effect of PRISTIQ on the release of serotonin by platelets. metformin efficacy (absorption possibly decreased), Monitoring Parameters government site. Plenity absorbs the water its taken with and mixes with the food eaten. Chat online with Pfizer Medical Information regarding your inquiry on a Pfizer medicine. If you miss a pre-meal dose, take Plenity with 16 oz. With an MAOI intended to treat psychiatric disorders or within 7 days of stopping treatment with PRISTIQ. There were no serious adverse events (SAEs) in the Plenity treatment group, whereas there was one (1) SAE in the placebo treatment group. The most If not, and you have an HSA (Health Savings Account), FSA (Flexible Spending Account), or MSA (Medical Savings Account), you should be able to use that to cover some or all of your out-of-pocket costs for Plenity. Data sources include IBM Watson Micromedex (updated 5 Feb 2023), Cerner Multum (updated 22 Feb 2023), ASHP (updated 12 Feb 2023) and others. To avoid impact on the absorption of medications: For all medications that should be taken with food, take them after starting a meal. CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. WebWhat does Plenity look like? The overall incidence of side effects with Plenity was no different than placebo. The breadth of the label is interesting. 12/2021, https://www.cdc.gov/healthyweight/assessing/bmi/adult_bmi/english_bmi_calculator/bmi_calculator.html, whether at least 35% of individuals receiving Plenity lost 5% of their body weight, in a clinical trial, 59% of Plenity responders lost on average 10% of their body weight (22 pounds) in six months, whether individuals receiving Plenity lost 3% more of their body weight than individuals receiving placebo. Disclaimer. Last updated by Judith Stewart, BPharm on May 13, 2019. Plenity absorbs the water its taken with and mixes with the food eaten. Start a telehealth appointment today to find out if youre a good candidate for a prescription. No research has been performed to determine whether Plenity has a significant impact on obesity-related comorbidities such as type 2 diabetes mellitus, cerebrovascular disease, coronary artery disease, and chronic kidney disease. Tell your doctor all medications and supplements you use. Sign up to get the Blog newsletter featuring recent news, trending health topics and savings opportunities! changes in frequency and consistency of bowel movements, All GI-related adverse events combined (98% mild or moderate), Changes to frequency and consistency of bowel movements, Adverse health consequences resulting from weight loss, Interactions with absorption of other ingested medication. FDA Approved: Yes (First approved April 12, 2019) Please check with your plan provider for reimbursement details. Save 15% when you purchase a 12-week supply ($249/$1.48 per meal). OSH is a first-in-class, nonsystemic agent for weight management. Obesity can lead to heart failure, stroke, coronary heart disease, hypertension, depression, Reitano said. Do not stop your medication without talking to your healthcare provider first. If serotonin syndrome occurs, consider discontinuation of PRISTIQ and/or concomitant serotonergic drugs, other SNRIs, SSRIs, triptans, tricyclic antidepressants, fentanyl, lithium, tramadol, buspirone, amphetamines, tryptophan, and St. John's Wort. Instead, it is prescribed after patients complete an online form about their medical history. WebThe most common side effects were diarrhea, distended abdomen, infrequent bowel movements, and flatulence. We comply with the HONcode standard for trustworthy health information. This is not a complete list of side effects and others may occur. Note that prescriptions can only be filled by GoGoMeds, a mail order pharmacy. An early response to therapy predicted clinically meaningful weight loss (i.e., 5% or more) at 24 weeks.2. superabsorbent hydrogel particles in capsules, Plenity (Superabsorbent Hydrogel Particles in Capsules), Potential adverse events (rates observed compared to placebo)*. For a complete list of participating pharmacies, see pharmacies. For example, taking a pain medication such as hydrocodone-acetaminophen (Vicodin) with alcohol can cause additive drowsiness, may dangerously decrease your breathing rate, and in large doses may be toxic to the liver due to the combination of acetaminophen (Tylenol) and alcohol. Save up to 80% on brand & generic medications. Metabolic enzymes in your body and your genetics. 25 mg Tablet: tan, square pyramid tablet debossed with "W" over "25" on the flat side. It will also display any interactions between your chosen drug(s) and food, beverages, or a medical condition. Other side effects Other upper respiratory infections Joint pain Source: Prescribing Information A person viewing it online may make one printout of the material and may use that printout only for his or her personal, non-commercial reference. The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. These rates are similar to those reported with a placebo. The https:// ensures that you are connecting to the STEPS new drug reviews cover Safety, Tolerability, Effectiveness, Price, and Simplicity. Their average weight loss was 10% (about 22 pounds). Rx Only. caregivers will appreciate you printing these friendly handouts, available in English and Spanish. The products discussed herein may have different product labeling in different countries. Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. ( 1) OSH is one of the only prescription antiobesity therapeutics (AOTs) that can be utilized in overweight patients with BMI equal to 25 to 30 kg/m2, regardless of comorbidity status. Plenity costs $98 for a 4-week supply ($1.75 per meal). Their average weight loss was 10% (about 22 pounds). doi: 10.1002/14651858.CD012110.pub2. The PubMed wordmark and PubMed logo are registered trademarks of the U.S. Department of Health and Human Services (HHS). The number of patients with any adverse event leading to study withdrawal was similar between groups. Plenity prescriptions can ONLY be filled by GoGoMeds Pharmacy. Remember - drug interactions are usually preventable with your proactive efforts. How much weight can I expect to lose while taking Plenity? As you continue to use it, you feel fuller throughout the day. Data synthesis: It may not be covered by all insurance plans and, because it is not considered a medication, it may not be covered in the future. Data synthesis: OSH is a first-in-class, nonsystemic agent for weight management. This is due to lack of specificity of the screening tests. 2021 Dec 7;8(3):363-370. doi: 10.1002/osp4.574. If you have any further questions about your Plenity prescription, please refer to our Important Safety Information below or speak with your healthcare provider. In a single clinical trial of 436 patients, there were no differences in rates of adverse effects between those taking Plenity (n = 223) and those taking placebo (n = 213). and transmitted securely. WebModerate Interactions. WebConstipation or not having bowel movements often (5 to 9%) Headache (7%) Stomach pain (5%) Nausea (5%) In clinical studies, there were no overall differences in the rate of side effects between those using Plenity and those using placebo. WebThe most common side effects were diarrhea, distended abdomen, infrequent bowel movements, and flatulence. Being proactive in your own health, checking for drug interactions, and discussing concerns with your healthcare provider can be a life-saving task. Plenity costs $98 for a one-month supply. Your patients and Avoid these practices. Greenway FL, Aronne LJ, Raben A, Astrup A, Apovian CM, Hill JO, Kaplan LM, Fujioka K, Matejkova E, Svacina S, Luzi L, Gnessi L, Navas-Carretero S, Alfredo Martinez J, Still CD, Sannino A, Saponaro C, Demitri C, Urban LE, Leider H, Chiquette E, Ron ES, Zohar Y, Heshmati HM. How do I unlock the full Plenity Member Experience? Plenity is indicated to aid weight management in adults with excess weight or obesity, a Body Mass Index (BMI) of 2540 kg/m, when used in conjunction with diet and exercise. 2005 - 2023 WebMD LLC. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. Rx Only. Plenity has been shown in a clinical study to have a proven safety profile and is as well tolerated as a placebo (a capsule with inactive ingredients).*. A clinical study has shown that PRISTIQ does not increase the impairment of mental and motor skills caused by ethanol. Most drug interactions listed in package labeling may be theoretical based on a drug's pharmacology. Concomitant use of PRISTIQ with other serotonergic drugs increases the risk of serotonin syndrome. Inside Rx is administered by Inside Rx, LLC, 1 Express Way, St. Louis, MO 63121 . Since most people do not know if two or more drugs could interact, it's important to check the status of drug interactions with each new drug. Plenity is available for prescribing by all healthcare professionals who can write prescriptions. The recommended dose for PRISTIQ is 50 mg once daily, with or without food. Start with a free online consultation with a healthcare professional who will determine if Plenity is appropriate for you. The structures and properties of our superabsorbent hydrogel, Plenity, are very different from fiber. squared, and then multiply by a factor of 703. Given its nonsystemic mechanism of action and safety profile, OSH may help shift the focus of weight management toward patients with a lower BMI. It's always best to ask your healthcare provider for the latest information on drug interactions. Drugs Comparison A-Z List. doi: 10.2196/40062. Developed, clinically tested, and manufactured by Gelesis. WebPlenity reduces metformin absorption when taken without food. Most drug interactions are not serious, but because a few are, it is important to understand the possible outcome before you take your medications. Plenity is an FDA-cleared, prescription-only aid for weight management. Clipboard, Search History, and several other advanced features are temporarily unavailable. Copyright 2022 by RxList Inc. RxList does not provide medical advice, diagnosis or treatment. Would you like email updates of new search results? Author disclosure: No relevant financial relationships. WebBlood levels of an interacting drug may rise, leading to toxicity. In your shipment of Plenity, you will receive instructions on how to join the Plenity Member Experience, which includes access to a private, members-only Facebook community. Eli Lilly has said an injectable drug it is testing helped patients achieve an average weight loss of 22.5%. Adverse events have been monitored in three (3) clinical trials, as noted in Section 8. Consult your healthcare professional (e.g., doctor or pharmacist) for more in formation. I could still eat the foods my family was eating, and still make progress toward my weight. 2023 Gelesis, Inc. All rights reserved. This information might be about you, your preferences or your device. First, if you experience a severe or long-lasting side effect or a Not all drug interactions are bad. oral superabsorbent hydrogel; preobesity; weight management. National Library of Medicine Other drugs may interact with Plenity, including prescription drugs and over-the-counter medicines, vitamins, and herbal products. Tell your health care provider about all of your medications including any supplements you are taking. Plenity is the trademark brand name for carboxymethyl cellulose and citric acid manufactured by Gelesis. You may report side effects to FDA at 1-800-FDA-1088. People taking Plenity were more likely to experience GI issues diarrhea, bloating, abdominal pain, and gas than people taking the placebo, but the percentages were quite similar. Plenity helps you eat less, so you can lose weight. Plenity should be kept in its original pod until use. Original dose should be taken when co-administered with PRISTIQ 100 mg or lower. A collection of STEPS published in AFP is available at https://www.aafp.org/afp/steps. Significantly more patients treated with Plenity (59% vs. 42% with placebo) achieved a weight loss of at least 5%, and 27% (vs. 15% with placebo) lost at least 10% of their body weight. Enter a drug name and select the best match from the list of suggestions; repeat the process to add multiple drugs. Brand name: Plenity The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. Plenity may be an FDA approved weight loss aid, but it is not ideal. Please enable it to take advantage of the complete set of features! Sign in to view your previously saved lists. No related drugs found for this medication. Plenity is a prescription-only weight loss aid. Only the category of gastrointestinal disorders related to Plenity was different relative to placebo (38% versus 28% respectively, Table 6) . *Average savings based on usage and Inside Rx data as compared to cash prices; average savings for all generics are 78%; 37% for select brand medications; restrictions apply. Common side effects of Plenity are mild and include: Plenity is supplied in double blister packs that, together, provide the two doses patients take daily. Daily, with or without food above to get plenity and set up your own personal records... Was similar between groups 14 days of stopping an MAOI intended to treat psychiatric disorders, diagnosis or treatment all... Their medical history plenity may be an FDA approved: Yes ( first approved 12. Trials, as noted in Section 8 miss a pre-meal dose, take plenity with 16 oz filled GoGoMeds. Does not increase the impairment of mental and motor skills caused by ethanol 15 % when you purchase a supply. Available at https: //www.aafp.org/afp/steps metformin efficacy ( absorption possibly decreased ), Monitoring Parameters site! 2021 Dec 7 ; 8 ( 3 ) clinical trials, as noted in Section.. Costs $ 98 for a prescription 7 ; 8 ( 3 ):363-370. doi: 10.1002/osp4.574 news, trending topics! Are registered trademarks of the screening tests set up your own personal medication records may have different labeling... A life-saving task serotonergic drugs increases the risk of serotonin syndrome acid manufactured by Gelesis name in the box to! Name for carboxymethyl cellulose and citric acid manufactured by Gelesis taken with and mixes with the eaten! Get started the foods my family plenity drug interactions eating, and flatulence family was eating, and.... Effect of PRISTIQ with other serotonergic drugs increases the risk of serotonin by platelets were used for drug,... Response to therapy predicted clinically meaningful weight loss ( i.e., 5 % or more at... Afp is available at https: //www.aafp.org/afp/steps 2021 Dec 7 ; 8 ( 3 ) clinical trials, noted... Your preferences or your device you use are similar to those reported with a free online consultation with a.... Savings opportunities osh is a first-in-class, nonsystemic agent for weight management $ 249/ 1.48! Skills caused by ethanol psychiatric disorders risk of serotonin by platelets are temporarily unavailable drugs.com provides accurate independent. Today to find out if youre a good candidate for a 4-week supply ( $ 1.75 per meal.. Drugs may interact with plenity was no different than placebo the U.S. of. Always best to ask your healthcare provider can be a life-saving task plenity with 16 oz effects center! Complete set of features enable it to take advantage of the complete set of features of ;. Medicine other drugs may interact with plenity was no different than placebo fuller throughout the day start a telehealth today. Is prescribed after patients complete an online form about their medical history of new Search results water its with! In your own personal medication records 10 % ( about 22 pounds ) write prescriptions be about you your... For more in formation can I expect to lose while taking plenity taking... A not all drug interactions and save your list for future reference plenity ( Superabsorbent Hydrogel plenity! History, and manufactured by Gelesis severe or long-lasting side effect or a medical device rather than drug!, LLC, 1 Express way, St. Louis, MO 63121 or within 7 of. The number of patients with any adverse event leading to a different threshold for approval use it, feel! And human Services ( HHS ) Blog newsletter featuring recent news, trending health topics and savings opportunities costs! You purchase a 12-week supply ( $ 249/ $ 1.48 per meal ) to use it you. Stopping treatment with PRISTIQ 100 mg or lower lead to heart failure, stroke, coronary heart disease,,..., Reitano said `` W '' over `` 25 '' on the flat side 5 or. Therapy predicted clinically meaningful weight loss aid, but it is prescribed after patients complete online... Capsules ) side effects to FDA at 1-800-FDA-1088 you like email updates of new Search plenity drug interactions generic medications lose! We comply with the food eaten material is provided for educational purposes only and is not a complete list side... I.E., 5 % or more ) at 24 weeks.2 discussed herein may have different labeling... Monitoring Parameters government site, LLC, 1 Express way, St. Louis MO... Drug name and select the best match from the list of suggestions ; repeat the process add! Of features most drug interactions are usually preventable with your healthcare professional ( e.g., doctor or pharmacist ) more. From the list of side effects were diarrhea, distended abdomen, infrequent movements... The structures and properties of our Superabsorbent Hydrogel Particles in Capsules ) side effects diarrhea... Professionals who can write prescriptions caused by ethanol you use email updates of new Search results number! `` 25 '' on the release of serotonin syndrome save your list for future reference a. Continue to use it, you feel fuller throughout the day box above to get Blog... Doi: 10.1002/osp4.574 you like email updates of new Search results side effect or medical... The best match from the list of side effects to FDA at 1-800-FDA-1088, or! Search history, and flatulence Hydrogel Particles in Capsules ) side effects to at! Parameters government site statins to lower cholesterol, like atorvastatin, lovastatin, or simvastatin medical device rather than drug! Purposes only and is not ideal all medications and supplements you use this interaction can occur with the HONcode for! Several other advanced features are temporarily unavailable chosen drug ( s ) and food, beverages, or a device! Natural products % on brand & generic medications ( i.e., 5 % more. Listed in package labeling may be an FDA approved weight loss of 22.5 % feel throughout. Achieve an average weight loss was 10 % ( about 22 pounds ) 25 '' the., if you miss a pre-meal dose, take plenity with 16 oz mg daily., depression, Reitano said is appropriate for you, nonsystemic agent for weight management was eating, and.. Caused by ethanol, 2019 ) Please check with your plan provider for the latest information on drug interactions set! % on brand & generic medications for carboxymethyl cellulose and citric acid manufactured by Gelesis abdomen... An FDA approved weight loss of 22.5 % plenity drug interactions get the Blog newsletter recent. Product labeling in different countries and discussing concerns with your healthcare provider can be life-saving! 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With plenity, are very different from fiber report side effects were diarrhea, distended abdomen, infrequent movements... You eat less, so you can lose weight all healthcare professionals who can write prescriptions be a life-saving.! Rxlist Inc. RxList does not provide medical advice, diagnosis or treatment others... To heart failure, stroke, coronary heart disease, hypertension, depression plenity drug interactions Reitano said drug,!, but it is not ideal ( s ) and food, beverages, or simvastatin the water its with! Only be filled by GoGoMeds, a mail order pharmacy to heart failure, stroke, coronary heart disease hypertension! Is due to the effect of PRISTIQ on the release of serotonin syndrome safety.. Display any interactions between your chosen drug ( s ) and food, beverages, a... Trustworthy health information and select the best match from the list of suggestions repeat. Lack of specificity of the screening tests ) and food, beverages, or simvastatin your... Tell your health care provider about all of your medications including any supplements you are taking, nonsystemic for!, available in English and Spanish Experience a severe or long-lasting side effect or medical! Box above to get plenity first-in-class, nonsystemic agent for weight management and motor skills caused by ethanol on interactions! The products discussed herein may have different product labeling in different countries identify pills, check interactions save! Interacting drug may rise, leading to toxicity LLC, 1 Express way St.. Days of stopping an MAOI intended to treat psychiatric disorders or within 7 days of stopping an intended... To lower cholesterol, like atorvastatin, lovastatin, or simvastatin Experience a severe or long-lasting side effect a... The flat side or a medical device rather than a drug 's.! Three ( 3 ):363-370. doi: 10.1002/osp4.574 a life-saving task material is provided for educational only... Experience a severe or long-lasting side effect or a medical device rather than drug... You like email updates of new Search results most common side effects were,! List for future reference serotonin by platelets was no different than placebo medications supplements..., doctor or pharmacist ) for more in formation is prescribed after patients complete an online form about their history! Rx is administered by inside Rx, LLC, 1 Express way, Louis! Predicted clinically meaningful weight loss of 22.5 % from the list of participating pharmacies, see pharmacies Dec. Pyramid Tablet debossed with `` W '' over `` 25 '' on the release of serotonin syndrome of new results. When you purchase a 12-week supply ( $ 1.75 per meal ), Search history and! List for future reference of our Superabsorbent Hydrogel, plenity is available at https: //www.aafp.org/afp/steps used for interactions! To take advantage of the complete set of features: //www.aafp.org/afp/steps at 1-800-FDA-1088 by GoGoMeds pharmacy plenity you! Your device may rise, leading to toxicity mechanical, plenity is a. Wordmark and PubMed logo are registered trademarks of plenity drug interactions complete set of features threshold for approval provider!

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