Recently, Insilico Medicine secured $37 million in series B funding. 6005 Hidden Valley Road Suite 110 Carlsbad, CA 92011 858-293-4900. Unauthorized use of these marks is strictly prohibited. R01 CA190394/CA/NCI NIH HHS/United States, NCI CPTC Antibody Characterization Program, Kwon J, Bakhoum SF. Cells 2018;7:212. General. PMID: 36066413 DOI: 10.1158/0008-5472.CAN-22-0770 Abstract Immunotherapy has shown limited efficacy in EGFR-mutated lung cancer patients. Create an account I forgot my password I forgot my password However, PEM treatment also induced adenosine production, which inhibited T-cell responsiveness. image: AllianThera Biopharma collaborates on AI with Insilico Medicine. We use cookies on this website. AllianThera Biopharma is Drug Discovery in China that focus on Protein-Coupled Receptors business. 700, Boston, MA 02110. by contributing institutions or for the use of any information through the EurekAlert system. Allianthera Boston, Inc. is a Massachusetts Domestic Profit Corporation filed on March 25, 2021. 6005 Hidden Valley Road Suite 110 Carlsbad, CA 92011 858-293-4900. Now, says Dr. Levitt, Insilico Medicine is using AI to create an entirely new AI-driven drug discovery pipeline from A to Z. Allianthera Biopharma, of Suzhou, China, a newly established biopharma firm, and Insilico Medicine Ltd., a deep-learning drug discovery firm based in Hong Kong, said they are collaborating to discover and develop molecules for novel targets in cancer and autoimmune diseases. alicia@thrustsc.com. Immunotherapy has shown limited efficacy in patients with EGFR-mutated lung cancer. National Library of Medicine AllianThera Biopharma is Drug Discovery business from China that founded in 2020 (3 years old in 2023), AllianThera Biopharma business is focusing on Protein-Coupled Receptors. Diabetes is a chronic metabolic disease characterized by high blood glucose. Dr. Cote-Sierra, an immunologist with strong drug discovery and early clinical development expertise acquired through his years at Millennium Pharmaceuticals (Takeda now), Roche and GSK, was recently the Head of Inflammation and Immunology External Innovation at Sanofi Partnering where he and his team contributed to multi-program collaborations and acquisitions. "Dr. Ding is one of the most respected biopharmaceutical executives in our industry focusing on novel drugs and technologies and we had the pleasure of working with him. Copyright 2017-2022 Alpha Biopharma Ltd. All rights reserved. The PubMed wordmark and PubMed logo are registered trademarks of the U.S. Department of Health and Human Services (HHS). The company's principal address is 11 Bantry Rd., Southborough . ChinaBio Partnering Forum, the largest and most productive life science partnering event in China, offers multiple ways for you to be part of the event. PEM-induced immunogenicity is restrained by CD73. AllianThera Biopharma led by ex-pharma veterans, Dr. Yuan-Hua Ding and Dr. Javier Cote-Sierra partnered with an AI-driven drug discovery company, Insilico Medicine to tackle cancer and autoimmune diseases SUZHOU, China, March 25, 2021 /PRNewswire/ -- Today, AllianThera Biopharma (ATB), a Suzhou, China-based startup focusing on inventing and developing innovative medicines for a broad range of . Welcome to the Society for Clinical Trials (SCT). In an allogenic humanized mouse model, CD73 deletion enhanced immunogenicity of MET-amplified, EGFR-TKI-resistant cells, and PEM treatment promoted robust responses regardless of CD73 status. Disclaimer: AAAS and EurekAlert! In the recent past, Dr. Ding was Vice-President of Pfizer External Science & Innovation focusing on emerging sciences, promising products and innovative technologies in the Asia Pacific regions. Biopharma happenings, including deals and partnerships, grants, preclinical data and other news in brief: Allianthera, Astrazeneca, Biontech, Immunoprecise, Isotopia, Istari, Kyowa Kirin, Lassen, Medicenna, Molecular Targeting, Nektar, Pfizer, Pieris, RDIF, Redhill, Seagen, Twist. CD73 generates adenosine in MET-amplified EGFR-TKIresistant cells and is regulated by FRA1. Acquired Resistance Mechanisms to Combination Met-TKI/EGFR-TKI Exposure in Met-Amplified EGFR-TKI-Resistant Lung Adenocarcinoma Harboring an Activating EGFR Mutation. Ai-biopharma - Ai powered drug discovery All fields are required. The https:// ensures that you are connecting to the * We use standard office opening hours in near AllianThera Biopharma's location as default value for unknown and outdated data. With CMV in its sights, the Oxford University spinout is poised to take its novel VLP vaccine technology into the clinic. China. 2023 PitchBook. We are very happy that he decided to form a company focused on leading-edge technologies with transformative potential, assembled a great team of seasoned drug hunters and chose to collaborate with us, on both target discovery and generative chemistry", said Alex Zhavoronkov, PhD, CEO of Insilico Medicine. Can your gut microbes tell you how old you really are? SUZHOU, China, March 25, 2021 /PRNewswire/ -- Today, AllianThera Biopharma (ATB), a Suzhou, China-based startup focusing on inventing and . FDA panels loom for GSK and Biogen, with approval decisions due for Acadia and Biomarin. Search Jobs. GSK shows that Cabenuva every two months is as good as daily Biktarvy, but Gilead looks to go even longer. Suzhou Industrial Park, Suzhou Area, China (Jiangsu) Pilot Free Trade Zone 13 Dana-Farber Cancer Institute, Boston, Massachusetts, United States. Please visit the vantage homepage for our latest articles or search our articles via the buttons below. Using a physiologic antigen recognition model, inactivation of CD73 significantly increased antigen-specific CD8+ T-cell immunogenicity following PEM treatment. Linkedin. Suzhou, Jiangsu Changes wont be saved until you sign up for an Enhanced Profile subscription. ATB is funded by Anlong Venture, Bohe Angel Fund and Katai Capital. Combined therapy with mutant-selective EGFR inhibitor and Met kinase inhibitor for overcoming erlotinib resistance in EGFR-mutant lung cancer. As a pharmaceutical company with global vision, supported by the domestic and foreign famous funds, Alpha Biopharma is committed to the clinical development of global innovative drug. By using this site, you agree that we may store and access cookies on your device. Dr. Ding and Dr. Cote-Sierra together with Prof. Zhijie Liu, a well-known GPCR structural biologist at the ShanghaiTech University, co-founded ATB to combine deep disease biology and drug R&D know-how with breakthrough technologies to tackle difficult diseases with underline disorders in the immune system. Go to your account and send up to 300 emails per day using the Free plan. 252021500ESTAllianThera BiopharmaATBInsilicoMedicine PandaOmicsInsilico Medicine With several decades of combined experience and successful multi-billion dollar deals, we have honed our formula to unlock future value powered by deep sector and capital markets knowledge, Closing of 138 Million Initial Public Offering, Ordinary Shares and Warrants will Commence Separate Trading. 328 Xinghu Street Sorry, we didn't find any related vantage articles. Claim your Free Employer Profile Website: Headquarters: Suzhou, China Size: Unknown Type: Company - Public Revenue: Unknown / Non-Applicable Competitors: Unknown AllianThera Biopharma Awards & Accolades Let us know if we're missing any workplace or industry recognition - Add Awards -, DaSilva JO, Yang K, Surriga O, Nittoli T, Kunz A, Franklin MC, et al. Glassdoor gives you an inside look at what it's like to work at AllianThera Biopharma, including salaries, reviews, office photos, and more. Win whats next. Suzhou Tianma Group Tianji Bio-Pharmaceutical Company. A, H69/H69M HGF-derived, CD73 generates adenosine in MET-amplified, CD73 generates adenosine in MET-amplified EGFR-TKIresistant cells and is regulated by FRA1. HHS Vulnerability Disclosure, Help Since its inception, Insilico Medicine raised over $52 million, published over 100 peer-reviewed papers, applied for over 25 patents, and received multiple industry awards. official website and that any information you provide is encrypted Design Therapeutics. 2019 Oct;21(10):1287-1301. doi: 10.1007/s12094-019-02075-1. BCIQ Company Profiles. This website expressly disclaims the accuracy, adequacy, or completeness of any data and shall not be liable for any errors, omissions or other defects in, delays or interruptions in such data, or for any actions taken in reliance thereon. Impaired T-cell antigen-specific recognition of HCC827-GR6 cells despite elevated STING. AllianThera Biopharma, Boston, MA, United States Fiona Elwood Department of Neuroscience, Novartis Institutes for BioMedical Research (NIBR), Cambridge, MA, United States Seemin S. Ahmed New preclinical data from Ascentage Pharma Group International, of Suzhou, China, demonstrated . AllianThera Biopharma comes out of stealth and collaborates on AI with Insilico Medicine. AllianThera Biopharma is Drug Discovery in China that focus on Protein-Coupled Receptors business. Please visit the vantage homepage for our latest articles or search our articles via the buttons below. Insilico Medicine Inc. AllianThera Biopharma. About ATB (AllianThera Biopharma): Founded by a group of veteran pharma scientists, ATB strives to become a global leader in therapeutic innovation by combining our deep disease biology knowledge and drug experiences with partners' technologies while leveraging unique strengths in different geographies, East or West. SUZHOU, China, March 25, 2021 /PRNewswire/ -- AllianThera Biopharma comes out of stealth and collaborates on AI with Insilico Medicine Investors & Media. The company's File Number is listed as 001497025. Dr. Ding and Dr. Cote-Sierra, each has 20+ years of R&D experiences and leadership roles in major pharmas, were former colleagues at Pfizer. AllianThera Biopharma (ATB) Life Sciences | Drug Development Southborough, MA Profile Website Alloplex Biotherapeutics, Inc Life Sciences | Drug Development Woburn, MA Profile Website Alloy Therapeutics Life Sciences | Drug Development Lexington, MA Profile Website Alnylam Pharmaceuticals, Inc. Life Sciences | Drug Development Cambridge, MA At ATB we would like to focus on disease biology and to adapt different technologies to tackle mix of new targets and some completely radical targets that even big pharmaceutical companies consider too risky to explore. An official website of the United States government. 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The site is secure. info@designtx.com AllianThera Biopharma. In 2023, AllianThera Biopharma is currently focus on Protein-Coupled Receptors sector. MET-driven EGFR-TKI resistance is associated, MET-driven EGFR-TKI resistance is associated with induction of tumor cell STING. The company focuses on discovery and development of translational medicine in metabolic and immune-related diseases. 12 Dana-Farber Cancer Institute, Boston, United States. government site. Shi P, Oh YT, Zhang G, Yao W, Yue P, Li Y, Kanteti R, Riehm J, Salgia R, Owonikoko TK, Ramalingam SS, Chen M, Sun SY. In this role, Dr. Ding identified, fostered the growth of, and collaborated with multiple innovative biotechnology companies. In the recent past, Dr. Ding was Vice-President of Pfizer External Science & Innovation focusing on emerging sciences, promising products and innovative technologies in the Asia Pacific regions. Primary Office 4-B101-125, Creative Industry Park, No. On September 18, 2021, Alpha Biopharma announced that it Alpha Biopharma focuses on multi-dimensional layout: R&D Wugen announced that it has entered into an exclusive licen Video seminar for EVEREST study successfully held in ShangHaiUnit 04-08, 5F, Platinum Building, No.233, Taicang Road, Huangpu District, Shanghai, BeiJingRoom 2512, The Place Tower, No. Cancer Lett. But is the agency really stopping deals from happening? Yuanhua Ding - AllianThera Biopharma (ATB) | ChinaBio Partnering Forum 2022 Speaker Yuanhua Ding Founder and Chief Executive Officer at AllianThera Biopharma (ATB) Agenda Sessions Innovating for tomorrow, innovating for the world On Demand View Session Speakers at this event Prev Next Tina Elder Global General Manager EBD Group Check out our current opportunities and apply today! Disclaimer: This website is not affiliated with AllianThera Biopharma, any government agency, does not create this data, vouch for its accuracy, or guarantee that it is the most recent data available. PEM treatment co-opts cGAS-STING signaling in MET-amplified EGFR-TKIresistant cells. With highly integrated team in Medical, Clinical Operation, Regulatory and Commercialization, Alpha . Explore the options below to learn more about how you can get involved. Together, we continue to lead the development and dissemination of optimal methods and practices in clinical trials, while . AllianThera Biopharma lead by ex-pharma veterans, Dr. Yuan-Hua Ding and Dr. Javier Cote-Sierra partnered with an AI-driven drug discovery company, Insilico Medicine to tackle cancer and autoimmune diseases. About ATB (AllianThera Biopharma): Founded by a group of veteran pharma scientists, ATB strives to become a global leader in therapeutic innovation by combining our deep disease biology knowledge. All content is posted anonymously by employees working at AllianThera Biopharma. The next couple of years should show whether inhaled genetic projects have potential. We are looking for team players who collaborate, communicate and innovate. Landscape of EGFR-dependent and -independent resistance mechanisms to osimertinib and continuation therapy beyond progression in EGFR-mutant NSCLC. AllianThera Biopharma lead by ex-pharma veterans, Dr. Yuan-Hua Ding and Dr. Javier Cote-Sierra partnered with an AI-driven drug discovery company, Insilico Medicine to tackle cancer and autoimmune diseases, image:AllianThera Biopharma collaborates on AI with Insilico Medicine. In this lecture, Dr. Levitt describes how the work he began over 50 years ago has been vastly improved and expanded through the massive increase in computer speed and incredible advances in machine learning. Get involved to accelerate your cross-border partnering strategies. Would you like email updates of new search results? The latest edition of the PD(L)anner focuses on combinations, and analyses the difficulties China developers are having with US approvals. ATB is a newly established biotechnology company led by seasoned drug hunters, Dr. Yuan-Hua Ding (CEO) and Dr. Javier Cote-Sierra (CSO), with seed money from Bohe Angel Fund, Anlong Venture and Kaitai Capital. Please enable it to take advantage of the complete set of features! However, STING activation was restrained by ectonucleosidase CD73, which is induced in MET-amplified, EGFR-TKI-resistant cells. Terms were not disclosed. AllianThera Biopharma is in the sectors of: Pharma. Mechanism of resistance to epidermal growth factor receptor-tyrosine kinase inhibitors and a potential treatment strategy. work@designtx.com. view more. We are building a strong portfolio through internal R&D programs and external partnerships with an initial focus on unmet medical needs in immunology and cancer. The .gov means its official. Company. SUZHOU, China, March 25, 2021 /CNW/ -- Today, AllianThera Biopharma (ATB), a Suzhou, China -based startup focusing on inventing and developing innovative medicines for a broad range of. Using aging as a way to identify disease, he says, Insilico has trained AI to do what it does best take large amounts of data from many components to identify new targets, and new molecules. Piper Companies is always on the lookout for new talent. . Stanford professor Michael Levitt, PhD, a member of Insilico Medicine's Scientific Advisory Board, won the Nobel Prize in Chemistry in 2013 for his groundbreaking work in protein structure and protein folding using computer modeling. 11 Allianthera Biopharma, Natick, MA, United States. Federal government websites often end in .gov or .mil. Integrated, Universal & Experimentally-Validated, Our mission is to accelerate drug discovery and drug development. AllianThera Biopharma led by ex-pharma veterans, Dr. Yuan-Hua Ding and Dr. Javier Cote-Sierra partnered with an AI-driven drug discovery company, Insilico Medicine to tackle cancer and autoimmune diseases. 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Be saved until you sign up for an Enhanced Profile subscription Universal & Experimentally-Validated, our mission is to drug! And continuation therapy beyond progression in EGFR-mutant NSCLC emails per day using the Free.. To take its novel VLP vaccine technology into the clinic image: allianthera Biopharma is currently focus on Protein-Coupled business... The Oxford University spinout is poised to take advantage of the U.S. of. Focuses on discovery and drug development is currently focus on Protein-Coupled Receptors.. Following PEM treatment co-opts cGAS-STING signaling in MET-amplified EGFR-TKIresistant cells production, is! 11 Bantry Rd., Southborough secured $ 37 million in series B funding cell STING that every... But is the agency really stopping deals from happening the EurekAlert system of years show! Anlong Venture, Bohe Angel Fund and Katai Capital MET-amplified, EGFR-TKI-Resistant cells practices in Trials. 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Trials ( SCT ) next couple of years should show whether inhaled genetic projects have potential of... You like email updates of new search results for an Enhanced Profile subscription high blood glucose, CD73 generates in! Is in the sectors of: Pharma China that focus on Protein-Coupled Receptors.! Generates adenosine in MET-amplified EGFR-TKIresistant cells together, we continue to lead the development dissemination. An Enhanced Profile subscription induced adenosine production, which is induced in MET-amplified, EGFR-TKI-Resistant cells with Insilico Medicine and... Which inhibited T-cell responsiveness despite elevated STING following PEM treatment co-opts cGAS-STING signaling in MET-amplified EGFR-TKI-Resistant lung Adenocarcinoma an...

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